Abstract
Purpose :
To investigate the prevalence and the risk factors of diabetic retinopathy(DR)in the Lifeline Express Diabetic Retinopathy Screening Program (LEDRSP) among diabetes in China.
Methods :
Diabetic patients in 8 hospitals across mainland China were recruited in this program and received digital fundus photography from January 2014 to December 2014. The fundus photography were graded in the reading center of Joint Shantou International Eye Center according to the UK national retinopathy screening system.Sight-threatening diabetic retinopathy (STDR) was defined as preproliferative DR(R2), proliferative DR (R3) and/or maculopathy (M1).
Results :
Totally 6987 patients with diabetes were screened, and 6913 had fundus pictures for grading. The prevalence of any DR was 29.1% and ranged from 17.3% to 42.1% among eight hospitals. The prevalence of STDR was 12.7%. The most common DR status was R1(23.0%), followed by M1 (8.1%), R2 (3.9%) and R3(2.2%). Multiple logistic regression indicated that longer DM duration(OR, 1.21; 95% CI, 1.12-1.30, per year increase), higher HbA1C(OR, 1.45, 95% CI, 1.20-1.54, per % increase), higher systolic blood pressure (OR, 1.10; 95% CI, 1.06-1.14, per 1-mmHg increase) and higher total cholesterol(OR, 0.78; 95% CI, 0.66-0.90, per 1-mmol/L increase)were the risk factors of STDR.
Conclusions :
The prevalence of DR and STDR in DM patients was 29.1% and 12.7% respectively in China. Risk factors for STDR includes DM duration, HbA1C and higher systolic blood pressure, total cholesterol.
This is an abstract that was submitted for the 2016 ARVO Annual Meeting, held in Seattle, Wash., May 1-5, 2016.