OCT-ANGIOGRAPHY OF ANGIOID STREAKS

Abstract

Purpose : Standard multimodal imaging is known to be crucial for the management and follow-up of angioid streaks (AS). Optical coherence tomography angiography (OCT-A) is a new imaging technique that allows a better visualization of blood flow in the retina and in the choroid capillary network. This study analyzes the features of the AS on OCT-A.

Methods : We retrospectively analyzed 15 eyes of 9 subjects (6 males and 3 females, age 57±13) affected by AS, with and without choroidal neovascularization (CNV). All patients underwent standard multimodal imaging, including multicolor imaging, infrared retinography (IR), blue autofluorescence (BAF), fluorescence angiography (FA), spectral-domain (SD)-OCT and OCT-A (Angioplex™, CIRRUS HD-OCT models 5000, Carl Zeiss Meditec, Inc., Dublin, USA). We studied the features of AS on OCT-A and compared them with the findings of angiography and SD-OCT.

Results : The OCT-A revealed a total of 40 angioid streaks. Most of them (35 AS) appeared as a choriocapillary rarefaction, corresponding to an hypo-reflective area of the RPE-Bruch’s membrane complex on SD-OCT. Five AS were not clearly evident on OCT-A choriocapillary segmentation. Choroidal segmentation was found to be normal in all patients in correspondence if AS.

Conclusions : OCT-A is a promising and non-invasive imaging technology for the diagnosis and follow-up of AS. On OCT-A in most cases a rarefaction of the choriocapillary network is evident in correspondence of AS.

This is an abstract that was submitted for the 2016 ARVO Annual Meeting, held in Seattle, Wash., May 1-5, 2016.