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Atsushi Hayashi, Shinya Abe, Mari Miyakoshi, Takuya Nakagawa; Correlation of parameters of laser speckle flowgraphy and retinal oximeter in healthy subjects. Invest. Ophthalmol. Vis. Sci. 2016;57(12):1659. doi: https://doi.org/.
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© ARVO (1962-2015); The Authors (2016-present)
To examine correlations between parameters of laser speckle flowgraphy (LSFG) and parameters of retinal oximeter in the eyes of healthy subjects.
Thirty one eyes of 31 healthy volunteer people (18 male and 13 female, range 19 to 75 years old) were included in this study. They underwent ophthalmoscopy examinations and LSFG (Nidek, Aichi, Japan) and retinal oximetry using Oxymap T1 (Oxymap ehf, Reykjavik, Iceland). Mean blur rate (MBR), blowout time (BOT), and blowout score (BOS) of the optic disc and retinal blood flow (RFV), BOT, and BOS of retinal vessels were obtained with LSFG in each eye. Oxygen saturations and diameters of retinal vessels of the same portions as measured by LSFG were obtained with Oxymap T1 in each eye. The parameters were statistically analyzed by Spearman’s rank-order correlation test.
The BOT of the optic disc measured by LSFG was weakly correlated with the oxygen saturations of retinal arterioles in healthy subjects (Spearman correlation=-0.46, p=0.008). The RFV of retinal venules was weakly correlated with the oxygen saturations of retinal venules in healthy subjects (Spearman correlation=-0.41, p=0.0001). The RFV of retinal arterioles and venules were significantly correlated with the vessel diameters of retinal arterioles (Spearman correlation=-0.60, p=0.0001) and venules (Spearman correlation=-0.70, p=0.0001), respectively.
Blood flow parameters of BOT and RFV measured by LSFG were correlated with oxygen saturations and vessel diameters of retinal vessels measured by Oxymap T1 in healthy subjects.
This is an abstract that was submitted for the 2016 ARVO Annual Meeting, held in Seattle, Wash., May 1-5, 2016.
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