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Ismael Ávila-Lule, Alfredo Terán-Tejada, Nallely Ramos Betancourt, Josué David Rodríguez-Pedraza, Francisco Beltrán-Díaz De La Vega, Everardo Hernandez-Quintela; Methicillin-Resistant Staphylococcus Keratitis in a Referral Ophthalmology Center. Invest. Ophthalmol. Vis. Sci. 2016;57(12):2354. doi: https://doi.org/.
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© ARVO (1962-2015); The Authors (2016-present)
To evaluate the frequency of Methicillin-Resistant Staphylococcus (MRS) Keratitis in a referral Ophthalmology Center in Mexico City.
A retrospective, observational study was performed. Data was collected from medical charts of patients who attended from February 2014 to February 2015 with diagnosis of infectious keratitis and positive cuture for Staphylococcus spp. The data base was subsequently used to obtain basic demographic information and results of gram stains, bacterial cultures, sensitivity and, resistance to antibiotics. MRS were identified by being resistant to oxacillin and/or cefoxitin disk diffusion.
Two hundred-ninety four Staphylococcus spp were isolated from 294 patients with keratitis during the study period. A hundred-twenty six (42.9%) were methicillin resistant by oxacillin disk, and 55 (18.7%) by cefoxitin disk. The MRS isolates included S. epidermidis (n= 148), S. aureus (n=60), S. Haemolyticus (n=21), S. Saprophyticus (n=19), S. hominis (n= 13), S. intermedius (n=8), and others. The MRS corneal isolates displayed extensive antimicrobial resistance.
The emergence of Methicillin-resistant Staphylococcus strains is clinically relevant because their resistance to multiple antibiotics limits their treatment options. Moreover, the antibiotic susceptibility is decreasing, introducing new challenges regarding its treatment and making constant antibiotic surveillance a priority
This is an abstract that was submitted for the 2016 ARVO Annual Meeting, held in Seattle, Wash., May 1-5, 2016.
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