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Miao He, Hui Ding, Xingwu Zhong; Investigation of the Corneal Biomechanics in Healthy Chinese Subjects Using a Corneal Visualization Scheimpflug Technology. Invest. Ophthalmol. Vis. Sci. 2016;57(12):2369.
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© ARVO (1962-2015); The Authors (2016-present)
In vivo quantification of corneal biomechanics became local focus since the introduction of Corneal Visualization Scheimpflug Technology (CorVis ST) in recent years. The aim of this study was to evaluate corneal biomechanical properties in a Chinese healthy population using this device.
Healthy subjects with 20 years and older were enrolled. All eyes underwent complete ocular examinations, including slit-lamp examination, auto refractometer, intraocular pressure (IOP), and CorVis ST. Corneal biomechanical parameters included maximum deformation amplitude (MDA), first applanation time (A1T), first applanation length (A1L), first applanation velocity (A1V), second applanation time (A2T), second applanation length (A2L), second applanation velocity (A2V), highest concavity time (HCT), peak distance (PD), and central radius of curvature (CCR). The Pearson correlation analysis was used to evaluate the correlations of corneal biomechanical parameters with age, central corneal thickness (CCT), spherical equivalent of refractive error (SE), gender, and IOP.
150 subjects were included with a mean age was 56.4±6.5 years. Mean SE was -1.65±1.07 diopters, the mean IOP was 14.5±2. 4 mmHg. Mean CCT was 549.72±29.96mm. There were no significant differences in SE, IOP, or CCT between male and female. Mean deformation amplitude was 1.07 ±0.04 mm. Highest concavity time was 17.38 ± 0.10 mm. A1T, A2T were 7.16 ± 0.46 ms and 22.10 ±0.37 ms, respectively. Most (9/10) CorVis ST parameters were independently associated with IOP, but only 4 parameters (MDA, A1L, A2L, A2V) were significantly correlated with CCT or age. Gender and SE did not influence CorVis ST parameters.
The CorVis ST provided informative measurements of corneal biomechanical properties. No significant difference of corneal biomechanics existed between male and female. IOP, age, and CCT were correlated to corneal biomechanics.
This is an abstract that was submitted for the 2016 ARVO Annual Meeting, held in Seattle, Wash., May 1-5, 2016.
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