Abstract
Purpose :
To evaluate the change of intraocular pressure(IOP) and development of normal tension glaucoma in accordance with the various anthropometric measurements
Methods :
A standardized protocol was used to interview and perform ophthalmic examinations on every participant. 5899 people were included. Included participants were undergone the ophthalmic examinations including IOP and several examinations necessary for the International Society of Geographical and Epidemiological Ophthalmology(ISGEO) criteria to know normal tension glaucoma diagnosis. IOP were selected as the right eye in the healthy group. The various anthropometric measurement included body mass index(BMI), total body fat mass, total lean body mass, total non-bone lean body mass, appendicular skeletal muscle(ASM) mass, total body bone mass, waist circumference(WC).
Results :
Total subjects were 5899. 2552 subjects were men and 3347 subjects were women. Mean age was 48.30. Among various anthropometric measurements, BMI and WC were positive correlation with IOP, in men and women. Total fat mass, total lean body mass, total non-bone lean body mass, and total bone mass were positive correlation with IOP in women, but not for men. The ratio of total fat mass and total non-bone lean body mass was positive correlation(P=0.02) with IOP and had high β coefficient value (β=0.810) in women. In addition, the ration of ASM and weight, the ratio of total fat mass and BMI, and the ratio of total fat mass and total muscle mass and BMI were significantly associated with the development of normal tension glaucoma.
Conclusions :
Some anthropometric measurements were associated with IOP and the development of normal tension glaucoma. Therefore, women who had high proportion of fat mass compared to muscle mass with same BMI may have high IOP.
This is an abstract that was submitted for the 2016 ARVO Annual Meeting, held in Seattle, Wash., May 1-5, 2016.