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Richard B Rosen; Adaptive Optics Scanning Light Ophthalmoscopy Microangiography. Invest. Ophthalmol. Vis. Sci. 201657(12):.
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© ARVO (1962-2015); The Authors (2016-present)
Presentation Description :
Adaptive optics scanning light ophthalmoscopy currently offers 2 micron lateral resolution, which is 10 times that achieved with conventional imaging devices, permitting unparalleled in vivo viewing of the microvasculature of the retina. It is possible to see the lamellar details of vessel walls, including deposits on the inner luminal surfaces, structural features of capillaries, such as microaneurysmal dilations, and even individual cells, such as pericytes and red blood cells. A variety of confocal and non-confocal optical techniques, including offset pinhole, split-detection, motion contrast and fluorescein contrast-enhancement in both static and dynamic modes provide complementary perspectives which can help identify perfused and non-perfused capillary segments and blood flow anomalies. Quantitive analysis techniques can be used to reveal subtle evidence of microvascular change and longitudinal studies can provide dynamic near-histological details of the sequence of microangiopathic developments
This is an abstract that was submitted for the 2016 ARVO Annual Meeting, held in Seattle, Wash., May 1-5, 2016.
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