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Hyungseon Yeom, Na Hyun Kim, Jong Suk Song, Hyung Keun Lee, Hyeon Chang Kim; Sleep disturbance is associated with dry eye syndrome in a rural population in Korea : Study group for Environmental Eye Disease (SEED). Invest. Ophthalmol. Vis. Sci. 2016;57(12):2839.
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© ARVO (1962-2015); The Authors (2016-present)
To evaluate the association between sleep disturbance and dry eye syndrome (DES).
We conducted a cross-sectional survey of 437 (160 men and 277 women) participants who live in a rural island in Korea. The mean age of the participants was 65 years (range 43 to 92). We assessed their health status by a questionnaire, physical examinations and blood tests. Presence of DES was defined as Ocular Surface Disease Index score ≥ 13 points. Sleep disturbance was defined as having difficulty more than once a week either in falling asleep or in going back to sleep when awoken during night. Multiple logistic regression was used to analyze the association after adjusting for age, hypertension, diabetes, dyslipidemia, body mass index, smoking, alcohol drinking, exercise, menopause and sleep duration. All analyses were separated by sex.
The prevalence of sleep disturbance was 35.6% in men and 53.8% in women. The prevalence of DES was 26.9% in men and 48.0% in women. The unadjusted odds ratio (95% CI) of sleep disturbance according to the presence of DES was 3.21 (1.56 - 6.63) in men and 1.74 (1.08 - 2.82) in women. After adjusting other covariates the adjusted odds ratio (95% CI) was 3.04 (1.28 - 7.26) in men and 1.78 (1.08 - 2.92) in women.
Our findings suggest that sleep disturbance is associated with presence of DES in rural population. Further prospective study is required to reveal the causal relationship.
This is an abstract that was submitted for the 2016 ARVO Annual Meeting, held in Seattle, Wash., May 1-5, 2016.
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