Abstract
Purpose :
To analyze functional and anatomical corneal changes after corneal collagen cross-linking.
Methods :
41 eyes of 35 patients (25 male and 10 female) mean age 24 ±7 years affected by mono or bilateral progressive keratoconus were enrolled. All patients underwent corneal collagen cross-linking using epithelium-off technique. Corneal topography, anterior segment OCT and in-vivo confocal microscopy were used for the evaluation of corneal changes.
Results :
Compared to pre-treatment values, corneal curvature and corneal apex decreased (p>0,05), Best Corrected Visual Acuity (BCVA) improved from 20/32 to 20/25 (p<0,05), while Central Corneal Thickness (CCT) was unchanged at 6-month follow-up visit (p=0,9557). In-vivo confocal microscopy showed anatomical changes during follow-up.
Conclusions :
Our study highlights that corneal anatomical changes have led to improved visual function. This confirms the efficacy and safety of collagen cross-linking in patients with progressive keratoconus.
This is an abstract that was submitted for the 2016 ARVO Annual Meeting, held in Seattle, Wash., May 1-5, 2016.