Abstract
Purpose :
To evaluate the safety and efficacy of trans-epithelial accelerated corneal cross-linking (TE-ACXL) in children with progressive keratoconus.
Methods :
Prospective, consecutive, case-series of 23 eyes of 14 children who underwent TE-ACXL. Tomographic and refractive changes were analyzed at baseline and 1, 3, 6, 12 and 18 months postoperatively.
Results :
Follow-up ranged from 18 to 30 months with a mean follow-up time of 23.82 months ±3.15. Mean age was 13.7 years ±1.4 (range 11-16). Mean preoperative UDVA from 0.92 ± 0.45 logMAR (20/160) to 0.71 ± 0.40 logMAR (20/100) (p=0.001). Mean keratometry (Km) changed from 53.87 ± 6.03 to 53.00 ± 5.81 (p=0.001). Pachymetry was 433.64±38.09 microns before treatment and 430.09 ± 54.26 microns at last follow-up (p=0.30). The mean preoperative sphere was -5.58±2.48 D and -4.89±4.66 (p=0.11) at last follow-up; refractive cylinder and spherical equivalent from -5.58±2.48 to -5.02±2.23 (p=0.046) and -7.90±5.39 to -7.41±4.84 (0.043), respectively.
Conclusions :
Tomographic and refractive stability was shown in over 91% of eyes with progressive keratoconus who underwent TE-ACXL
This is an abstract that was submitted for the 2016 ARVO Annual Meeting, held in Seattle, Wash., May 1-5, 2016.