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Bronson Matthias LeClair, Howard V Gimbel, Joseph T Fan; Long Term Follow-up of Posterior Chamber Phakic Intraocular Lens for Myopia. Invest. Ophthalmol. Vis. Sci. 2016;57(12):3107.
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© ARVO (1962-2015); The Authors (2016-present)
Some authors have suggested that an increased rate of anterior subcapsular cataract (ASC) development may occur with increasing age and decreasing anterior chamber depth at the time of implantable collamer lens. This correlation has not been well studied. We performed a retrospective observation study of 1693 eyes, comparing the rate of ICL removal with cataract extraction and intraocular lens placement (CE-IOL) as a result of ASC, with age and anterior chamber depth.
We analyzed 1693 eyes implanted with the ICL V4 model (Visian ICL; STAAR surgical) from 2000 to 2012 at the Gimbel Eye Centre, Calgary. Myopic and astigmatic patients aged 19 and above, with no prior history of cataracts were selected for this study. Parameters including the rate of ICL removal with cataract extraction, age, sex, length of follow-up, and measurement of anterior chamber depth were collected. Retrospective statistical analysis was performed.
Of the 1693 eyes included in this study, a total of 48 eyes underwent ICL removal with CE-IOL. The length of follow-up varied between 2 years to 14 years. Of those 48 eyes, 37 (77%) were older than 45 years at the time of ICL implantation. There was a significant positive correlation (r2=0.22, P = 0.002) between age and the rate of ASC development leading to CE-IOL. Of those 48 eyes, 31 (65%) had an ACD of less than 3.00 mm and there was a significant negative correlation (r2=0.26, P = 0.0003) between ACD the rate of ASC development leading to CE-IOL. All 48 CE-IOL eyes had previously measured ICL vaults under 140 μm.
This retrospective study demonstrated that the rate of developing anterior subcapsular cataracts has a positive correlation with age, and a negative correlation with anterior chamber depth. These findings could offer patient specifc risk assessment of ASC development, based upon individual parameters.
This is an abstract that was submitted for the 2016 ARVO Annual Meeting, held in Seattle, Wash., May 1-5, 2016.
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