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Jason S. Kim, Eliott Kim, Elliot Crane, May Shum, David S Chu; The development of ocular complications in subjects diagnosed with intermediate uveitis. Invest. Ophthalmol. Vis. Sci. 2016;57(12):3314.
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© ARVO (1962-2015); The Authors (2016-present)
To analyze the development of ocular complications in subjects with intermediate uveitis, including cataracts, glaucoma, Cystoid Macular Edema (CME), band keratopathy, and papillitis.
Data from April 2003 to February 2015 was collected through a billing database of a tertiary care provider from subjects that were identified with intermediate uveitis. The collected data consisted of subject’s age, gender, systemic medical conditions, and laboratory test results. Calculations and statistical analyses were carried out using Microsoft Excel version 2013.
45 subjects with intermediate uveitis met study criteria (22 male, 23 female, age range 8-75 years, mean age 37 years at first visit). Mean and standard deviation of follow up time were 3.8 ± 3.5 years. 26 subjects (57.8%) developed cataracts. 18 subjects (40.0%) developed glaucoma. 8 subjects (17.8%) developed CME. 5 subjects (11.1%) developed band keratopathy. 8 subjects (17.8%) developed papillitis. Many subjects developed these ocular complications prior to arrival at our tertiary care center. 23 of the 26 subjects (88%) with cataracts developed them prior to their first visit at our center. 14 of the 18 subjects (78%) with glaucoma were diagnosed prior to their first visit. 5 of the 8 subjects (63.5%) with CME were also developed prior to their first visit. 5 of the 5 subjects (100%) with band keratopathy were developed prior to the first visit. 6 of the 8 subjects (75%) developed papillitis prior to the first visit. Some subjects developed multiple ocular complications. 2 subjects developed cataracts and CME. 1 subject developed cataracts and band keratopathy. 11 subjects developed cataracts and glaucoma. 2 subjects developed glaucoma and CME. 2 subjects developed band keratopathy, papillitis, and glaucoma. 1 subject developed papillitis and CME. 1 subject developed band keratopathy and CME. Overall, 34 out of 45 subjects (75.6%) developed one or more of these complications.
Intermediate uveitis may have some association with various ocular complications. The high rates of concurrent ocular disease found here argue that intermediate uveitis may be associated with these ocular diseases, such as cataracts, glaucoma, CME, band keratopathy, and papillitis. Detailed physical examinations and select imaging modalities should be used in the treatment of intermediate uveitis to monitor for these vision threatening complications.
This is an abstract that was submitted for the 2016 ARVO Annual Meeting, held in Seattle, Wash., May 1-5, 2016.
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