Abstract
Purpose :
To assess visual field loss as a whole and by sectors using Eye Suite (Haag Streit) and identify factors related to its progression.
Methods :
Retrospective case control study. 2547 visual fields of 317 eyes obtained during a median follow-up of 8.4 years (2.5-11.6) were assigned to the three groups: ocular hypertension (N=153), glaucoma (N=122; 64 incipient, 44 moderate and 14 advanced) and control (N=42). Changes produced over time in the mean defect (MD), diffuse defect (DD), local defect (LD) and loss variance (LV) were examined in a global trend and a cluster trend analysis by sectors. A logistic regression model was constructed to assess the effects of demographic factors, glaucoma or cataract surgery, laser treatment, number of antihypertensive drugs or treatment changes.
Results :
In 37.70% of the eyes with glaucoma MD showed significant worsening (p <0.05) to give a median progression rate of 0.7 (0.4-1.32) dB/year. Greatest field loss during follow-up was produced in the temporal-inferior sector and least in the upper nasal sector. Patients requiring a larger number of antihypertensive drugs showed a higher progression rate than those on fewer medications. Cataract surgery was the independent factor that most affected MD progression (p = 0.017; OR = -3.61).
Conclusions :
Glaucoma patients showed the highest median rate of visual field loss progression which was more evident in the inferior temporal sector. Cataract surgery should be considered in any glaucoma progression analysis.
This is an abstract that was submitted for the 2016 ARVO Annual Meeting, held in Seattle, Wash., May 1-5, 2016.