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Anna Shengelia, Peter H Derr, Celso Tello; Evaluation of pattern ERG responses using various electrodes. Invest. Ophthalmol. Vis. Sci. 2016;57(12):3943. doi: https://doi.org/.
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© ARVO (1962-2015); The Authors (2016-present)
To evaluate how the Diopsys-NOVA ERG skin electrode, DTL electrode and the Ag/AgCl electrode affect the Pattern ERG response.
Five subjects with normal vision were tested with Diopsys NOVA system three times with each of the following electrodes: a Diopsys NOVA-ERG skin electrode, a DTL electrode and a Silver/Silver Chloride cup electrode. Each test consisted of the skin being prepared and a new electrode being applied. A two way Analysis of Variance (ANOVA) statistical analysis was performed on the resulting data.
For the PERG P50 amplitude parameter, the Diopsys electrode had the smallest standard deviation (0.722) whereas the DTL had the largest standard deviation (3.879). The following summarizes the results: There was no significant main effect for the subjects group (F (4, 44) = 2.44, p =0.0634, Fcritical(4, 44) = 2.58), and there was a significant main effect for electrode group (F (2, 44) = 7.85, p = 0.0014, Fcritical (4, 44) = 3.21). For the PERG P50 latency parameter, the Ag/AgCl cup electrode had the smallest standard deviation (3.29) whereas the DTL had the largest standard deviation (10.18).<span style="mso-spacerun:yes"> </span>The following summarizes the results: There is a significant main effect for subjects group (F (4, 44) = 3.17, p =0.0241, Fcritical(4, 44) = 2.58), and there was no significant main effect for electrode group (F (2, 44) = 1.835, p = 0.1740, Fcritical (4, 44) = 3.21)
The Diopsys NOVA-ERG skin produced a significant improvement in recording the PERG amplitude parameter as compared to the DTL and Ag/AgCl cup electrodes. There was no loss of PERG latency information when the Diopsys NOVA-ERG electrode was used.
This is an abstract that was submitted for the 2016 ARVO Annual Meeting, held in Seattle, Wash., May 1-5, 2016.
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