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Zeliha Yazar, Ayse Metin Kayhan; Comparison of Corneal Topography, Optic Coherence Tomography, Macula Pigment Optic Density of High Myopic Eyes And Emmetropic Eyes in Terms of Visual Acuity, Axial Length, Posterior Segment Signs. Invest. Ophthalmol. Vis. Sci. 2016;57(12):4255.
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© ARVO (1962-2015); The Authors (2016-present)
To investigate relationship of myopia degree, axial length(AXL), posterior segment signs of high myopic subjects with corneal topography, optic coherence tomography(OCT), macula pigment optic density(MPOD).
The study group included 40 high myopic eyes(right eyes) which have – 6.00 D and over refractive error of 40 healty adults, control group included 40 emetropic eyes(rigt eyes) of 40 healty adults. All subjects examined with refraction and,fundus examinations,corneal topograhy, AXL measurement,MPOD measurement,central macular thickness(MT), average MT, macular inner and outer segment analysis, ganglion cell complex(GCC) analysis, retinal nerve fiber layer(RNFL) analysis, subfoveal choroidal thickness(SCT) analysis with OCT. The data obtained from two groups was compared.
Mean refractive error was found -11,03±4,35 [(-6.00)-(-20.00)] D in myopic group.Central corneal thickness was similar in two groups(p=0.303).Anterior chamber volume,depth and degree was greater in high myopic eyes(p<0.001),there were positive relationship with refractive error degree and AXL(R=0.931,p=0.00001).In high myopic eyes average MT and macula outer segment thickness were reduced(p<0.001),central foveal thickness was increased(p=0.004),macula inner segment thickness wasn’t changed(p=0.223).There was inverse relationship between refractive error/ AXL and average MT,macula outer segment thickness;positive relationship with central foveal thickness and no relationship with macula inner segment thickness.RNFL was reduced in high myopics(p<0.001).There was inverse relationship between RNFL thickness and refractive error/AXL(R=0.523,p<0.05/R=0.597,p<0.05).GCC thickness,SCT were reduced in high myopic patients(p<0.001).Also there was inverse relationship between refractive error power/AXL and SCT (R=0.437,p<0.05/ R=0.535,p<0.05). MPOD was increased in high myopic subjects(p<0.001).
There were anterior and posterior segment changes of high myopic eyes secondary to anterior-posterior elongation of eye. These changes especially important in disorders that evaluated according to thickness analysis. If databases of high myopic eyes were installed to OCT machines and improvement of hardwares according to axial length changes of patients were approved, these all provide us better, reliable examinations.
This is an abstract that was submitted for the 2016 ARVO Annual Meeting, held in Seattle, Wash., May 1-5, 2016.
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