Investigative Ophthalmology & Visual Science Cover Image for Volume 57, Issue 12
September 2016
Volume 57, Issue 12
Open Access
ARVO Annual Meeting Abstract  |   September 2016
Multicolor and Optical Coherence Tomography Appraisal of Deep Retinal Capillary Ischemia
Author Affiliations & Notes
  • Rosa Dolz-Marco
    Institute for Health Research, University and Polytechnic Hospital La Fe,, Spain, Valencia, Valencia, Spain
    Macula Unit, University and Polytechnic Hospital La Fe, Valencia, Spain
  • LAURA MONJE-FERNANDEZ
    Macula Unit, University and Polytechnic Hospital La Fe, Valencia, Spain
    University Hospital Complex of León, Leon, Spain
  • María Andreu-Fenoll
    Macula Unit, University and Polytechnic Hospital La Fe, Valencia, Spain
    Institute for Health Research, University and Polytechnic Hospital La Fe,, Spain, Valencia, Valencia, Spain
  • Nestor Garcia-Marin
    Macula Unit, University and Polytechnic Hospital La Fe, Valencia, Spain
  • Roberto Gallego-Pinazo
    Macula Unit, University and Polytechnic Hospital La Fe, Valencia, Spain
    Retics Oftared (RD12/0034); Prevention, Early Detection And Treatment Of The Prevalent Degenerative And Chronic Ocular Pathology, Institute of Health Carlos III, Madrid, Spain
  • Footnotes
    Commercial Relationships   Rosa Dolz-Marco, Alcon (F), Heidelberg Engineering (F), Novartis (F); LAURA MONJE-FERNANDEZ, None; María Andreu-Fenoll, None; Nestor Garcia-Marin, None; Roberto Gallego-Pinazo, Alcon (F), Bayer (F), Heidelberg Engineering (F), Novartis (F)
  • Footnotes
    Support  none
Investigative Ophthalmology & Visual Science September 2016, Vol.57, 4261. doi:
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      Rosa Dolz-Marco, LAURA MONJE-FERNANDEZ, María Andreu-Fenoll, Nestor Garcia-Marin, Roberto Gallego-Pinazo; Multicolor and Optical Coherence Tomography Appraisal of Deep Retinal Capillary Ischemia. Invest. Ophthalmol. Vis. Sci. 2016;57(12):4261.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : To describe the morphometric features of different patterns of retinal arterial ischemia analyzed by high-definition optical coherence tomography (OCT) and Multicolor imaging technology

Methods : Patients with retinal arterial ischemic diseases were included in the present study. In all cases, a comprehensive ophthalmic examination was performed including ocular and systemic medical history details, and the measurement of visual acuity, intraocular pressure, and slit lamp anterior segment examination. Following pupil dilation, conventional color fundus photographs were obtained, and optical coherence tomography images combined with Multicolor images were acquired (HRA Spectralis, Heidelberg Engineering).

Results : A total number of 12 eyes of 12 patients (4 man and 8 women; age range:26-90 years) were included in the present analysis. Nine cases showed combined superficial and deep retinal capillary ischemia that appeared as a hyperreflective thickening of all the retinal layers except for the outer nuclear layer and the photoreceptor layer, and evidenced as intensively white in the Multicolor images. Three cases showed isolated deep retinal capillary ischemia that appeared as a hyperreflective thickening of the retina involving the area of the neurosensory retina within the outer plexiform layer and the inner plexiform layer, and evidenced as dark grayish in the Multicolor images.

Conclusions : Optical coherence tomography and Multicolor imaging techniques may be of great value in order to assess and differentiate the morphometric changes induced by different patterns of retinal arterial ischemia. The systemic and prognostic implications of this classification is highly relevant and therefore a precise diagnosis should be performed in the presence of retinal ischemic diseases.

This is an abstract that was submitted for the 2016 ARVO Annual Meeting, held in Seattle, Wash., May 1-5, 2016.

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