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Jesus Cabral, Flor Daniela Guzman-Iturbe, Alejandro Navas, Aida Jimenez-Corona, Enrique O Graue-Hernandez, Arturo J Ramirez-Miranda; Effects of Small-Incision Lenticule Extraction (SMILE) on Corneal Endothelial Cells. Invest. Ophthalmol. Vis. Sci. 201657(12):.
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© ARVO (1962-2015); The Authors (2016-present)
To investigate the corneal endothelial changes after SMILE procedure.
Prospective study, a total of 30 eyes of 15 patients with myopia ranging from -3.25 to -10.00 diopters (D) and astigmatism up to -3.50D were treated with SMILE. Endothelial cell density (ECD), and the coefficient of variation (CV), were measured preoperatively and at 1 day and 3 months postoperatively.
No eyes developed corneal edema or other complications. No significant changes were observed regarding ECD and CV at any visit point (p>0.05). Endothelial cell changes in terms of ECD, CV were not correlated with the amount of myopia or astigmatism.
SMILE showed improvement in visual acuity and no adverse effects to corneal endothelial cells were found.
This is an abstract that was submitted for the 2016 ARVO Annual Meeting, held in Seattle, Wash., May 1-5, 2016.
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