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Joanna Wasielica-Poslednik, Marcel Sebastian Sievers, Walter Lisch, Veronika Weyer, Norbert Pfeiffer, Adrian Gericke; Influence of contact lens wearing on whole corneal thickness and corneal epithelial thickness measured with Fourier-domain optical coherence tomography. Invest. Ophthalmol. Vis. Sci. 2016;57(12):4360. doi: https://doi.org/.
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© ARVO (1962-2015); The Authors (2016-present)
To investigate the effect of contact lens use on whole corneal thickness (CT) and corneal epithelial thickness (ET) measured with Fourier-domain optical coherence tomography (FD-OCT, RTVue).
Both eyes of 17 soft contact lens (SCL) wearers, 9 hard contact lens (HCL) wearers and 31 age- and sex-matched controls were included in this prospective study. CT and ET were measured with FD-OCT in 9 areas: corneal vertex, 4 paracentral and 4 peripheral zones in control subjects and in CL-wearers immediately after discontinuing of CL. The second measurement was performed in controls and CL-wearers after five days of CL-discontinuation. At each visit, refraction error, best-corrected visual acuity, slit-lamp examination and Schirmer test were performed in both eyes of all subjects. Statistical analyses were conducted using ANOVA, Mann-Whitney test, t-test and Wilcoxon test.
ET differed relevantly in vertex and in paracentral zones between the individual groups (HCL < SCL < controls, p<0.05) at baseline. After five days of CL restriction, an increase of ET in vertex and in paracentral zones was noted in the HCL-wearers (p<0.05), but not in the SCL-wearers and in the control group. CT did not differ relevantly between the study groups at baseline [HCL > control > SCL (p>0.05)]. Five days of contact lens restriction had no relevant influence on CT, BCVA, refraction error and Schirmer test.
ET was relevantly thinner in vertex and in corneal paracentral zones in CL wearers compared to controls. A five day discontinuation of CL wearing led to an increase in ET, which was relevant in HCL-wearers.
This is an abstract that was submitted for the 2016 ARVO Annual Meeting, held in Seattle, Wash., May 1-5, 2016.
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