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Ji Won Kim, Young Jun Woo, Jin Sook Yoon; Association between Graves’ orbitopathy and ocular hypertension prevalence. Invest. Ophthalmol. Vis. Sci. 2016;57(12):4557. doi: https://doi.org/.
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© ARVO (1962-2015); The Authors (2016-present)
To determine the prevalence and clinical features of Graves’ orbitopathy(GO) patients diagnosed as ocular hypertension and open angle glaucoma.
In this corss-sectional analytic study, 1,128 patients with GO who visited Yonsei University College of Medicine between January 2009 and December 2014 were recruited. Complete ophthalmic examination, intraocular pressure, optic disc photography, visual field with Humphrey visual field analyzer, and retinal nerve fiber layer thickness measurement with optical coherence tomography were performed. Odds ratios(OR) and 95% confidence intervals(CIs) were used to quantify the association between a diagnosis of ocular hypertension and clinical features of GO.
A 6.8% prevalence of ocular hypertension (77 patients) and a 1.6% prevalence of glaucoma (18 patients) was observed. When considering only patients older than 40 years, the prevalence of ocular hypertension and glaucoma was 9.5% and 2.7%, respectively. Twenty nine of 1,128 patients(2.6%) developed compressive optic neuropathy; high intraocular pressure was detected in 10 of them (0.9%). Of the factors evaluated, sex(males), duration of GO, Clinical activity score≥3, extraocular muscle involvement, lid retraction were associated with prevalence of ocular hypertension in GO.
Prevalence of ocular hypertension in GO patients(9.5% in age≥40) was higher than that in general Korean polulation(0.6% in age≥40), but open angle glaucoma in GO patients(2.7% in age≥40) was similar to that in the general population(3.5% in age≥40).
This is an abstract that was submitted for the 2016 ARVO Annual Meeting, held in Seattle, Wash., May 1-5, 2016.
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