Abstract
Purpose :
To evaluate the retinal venous pulsation using fourier-domain doppler optical coherence tomography (Doppler OCT flowmeter,Topcon, japan) in patients with central retinal occlusion (CRVO).
Methods :
Doppler OCT flowmeter was used in 4 patients with CRVO. We measured retinal veins blood velocity within 1 disc diameters from the optic disc and assessed the ratio Vmax (maximum blood velocity)/Vmin (minimum blood velocity).
Results :
Of 2 patients with CRVO and Impending-CRVO, the Vmax/Vmin were 2.0 and 2.7, respectively in diseased eye. However, the Vmax/Vmin were 1.8 and 1.7, respectively in healthy eye.
Of 2 patients with CRVO and Hemi-CRVO with macular edema, the Vmax/Vmin were 2.2 and 2.0, respectively in diseased eye. After treatment with ranibizumab (RBZ), the Vmax/Vmin were 1.9 and 1.8, respectively in diseased eye.
Conclusions :
In all patients with CRVO, the Vmax/Vmin of diseased eye was more than 2.0 and that of healthy eye was below 2.0. In addition, RBZ decreased Vmax/Vmin and it is below 2.0.The current study first indicated that venous pulsation of retinal veins may shed light on the pathogenesis of CRVO, which needs to be proven in future studies.
This is an abstract that was submitted for the 2016 ARVO Annual Meeting, held in Seattle, Wash., May 1-5, 2016.