Abstract
Purpose :
We investigate the potential of high-speed (>100Hz) wide field of view (>3°) retinal imaging with a high performance adaptive optics platform.
Methods :
PARIS (Paris Adaptive-optics Retinal Imaging & Surgery) group gathers physicians and physicists around an experimental adaptive optics (AO) platform, located inside Quinze-Vingt Ophtalmology hospital, with a direct access to patients. The AO platform consists in a custom made AO flood illumination ophtalmoscope, featuring a fast AO loop (faster than 60Hz), an 88 actuator deformable mirror (ALPAO) and a high speed SCMOS camera (Hammamatsu Orca Flash4-V2). It provides retinal video stacks acquired at more than 100Hz on 3° field of view with an 860nm SLD source (OMICRON).
Design was based on an original aberrometry campaign on 69 normal eyes from which an error budget analysis was made. In particular, the opportunity of stabilizing the pupil is discussed.
Results :
Continuous frame rates of up to 100 Hz were achieved for imaging 3 deg retinal patches. The adaptive optics software (custom made LabView+IDL) made possible to image subjects without dilation or cycloplegia, revealing for instance blood flow in capillaries.
Conclusions :
We demonstrated on several subjects high-speed (>100Hz) wide field of view (>3°) retinal imaging without dilation or cycloplegia. This high performance AO-platform will soon host innovative imaging instruments (starting in Spring 2016).
This is an abstract that was submitted for the 2016 ARVO Annual Meeting, held in Seattle, Wash., May 1-5, 2016.