September 2016
Volume 57, Issue 12
Open Access
ARVO Annual Meeting Abstract  |   September 2016
Comparison of higher-order aberrations following small incision lenticule extraction (SMILE) and wavefront-guided Femto-LASIK
Author Affiliations & Notes
  • Xiaoqin Chen
    Tianjin Medical University, Tianjin, China
    Tianjin Eye Hospital, Tianjin, China
  • Yan Wang
    Tianjin Eye Hospital, Tianjin, China
  • Jiamei Zhang
    Tianjin Medical University, Tianjin, China
  • Shunnan Yang
    Visual Performance Institue, Pacific University, Forest Grove, Oregon, United States
  • Xiaojing Li
    Qinghuangdao Hospital, Qinghuangdao, Hebei, China
  • Footnotes
    Commercial Relationships   Xiaoqin Chen, None; Yan Wang, None; Jiamei Zhang, None; Shunnan Yang, None; Xiaojing Li, None
  • Footnotes
    Support  National Science Foundation (No. 81470658) in China
Investigative Ophthalmology & Visual Science September 2016, Vol.57, 4863. doi:
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    • Get Citation

      Xiaoqin Chen, Yan Wang, Jiamei Zhang, Shunnan Yang, Xiaojing Li; Comparison of higher-order aberrations following small incision lenticule extraction (SMILE) and wavefront-guided Femto-LASIK. Invest. Ophthalmol. Vis. Sci. 2016;57(12):4863.

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      © ARVO (1962-2015); The Authors (2016-present)

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Purpose : To evaluate changes in high-order aberrations (HOAs) following SMILE and wavefront guided Femto-LASIK (WF-LASIK), and to investigate the relation between these changes and preoperative spherical equivalence (SE).

Methods : Fifty-one eyes of 28 patients were included in the study. The mean preoperative SE refraction was -5.50 diopters (D)±1.32 (SD) and -4.91 diopters (D)±2.34 (SD) in the SMILE and WF-LASIK group, respectively (t=1.045, p =0.305). Uncorrected distance visual acuity (UDVA), corrected distance visual acuity (CDVA), refractive error were measured before and 3 months after surgery to evaluate resultant visual comes. Also, Zernike coefficients of second- to sixth-order HOAs were measured and analyzed.

Results : Similar UDVA and CDVA were found after WF-LASIK (Mean ± SD: -0.02±0.05 and -0.05±0.04 logMAR respectively) and SMILE surgeries (-0.02±0.06 and -0.04±0.04 logMAR). There was significant difference in vertical coma (Z = -2.257, p = 0.024) between two groups after surgery although there were no difference in vertical or horizontal trefoil, horizontal coma, spherical aberration and total HOA. The preoperative SE was correlated to horizontal coma (r = -0.670, p = 0.001) in WF-LASIK and vertical coma (r=-0.520, p=0.003) in SMILE group after surgery.

Conclusions : Both SMILE and WF-LASIK in correcting myopia can achieved similar visual outcomes. For optical quality, however, specific changes were demonstrated since the principal and design is different which might cause the different wounding healing.

This is an abstract that was submitted for the 2016 ARVO Annual Meeting, held in Seattle, Wash., May 1-5, 2016.


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