Abstract
Purpose :
To report silent type 1 choroidal neovascular membrane (CNV) in Age-Related Macular Degeneration (ARMD) as detected by optical coherence tomography angiography (OCTA)
Methods :
Retrospective review of Split Spectrum Amplitude Decorrelation Angiography based OCTA, SD-OCT and fluorescein angiography (FA) results on patients with silent type 1 CNV in ARMD.
Results :
Eight eyes with wet ARMD were clinically quiet. FA showed no definite fluorescein leakage or increased fluorescein staining in the late phase. One eye showed a small retinal pigment epithelial detachment. SD-OCT showed no definitive intra- or sub-retinal fluid. However, OCTA detected blood flow in type I CNV in each eye. The size and vascular volume of the CNV varied. The contralateral eyes showed active type 1 CNV in 4, type 2 CNV in 1, treated and quiescent type 1 CNV in 1, and no CNV in 2. No silent CNV became active in follow-up examinations for over one year.
Conclusions :
OCTA successfully detected subclinical, silent CNVs in 8 ARMD patients. Although it is uncertain when and whether the silent CNVs will become active, detection of these subclinical CNVs by OCTA may prompt a more vigilant follow-up for these patients.
This is an abstract that was submitted for the 2016 ARVO Annual Meeting, held in Seattle, Wash., May 1-5, 2016.