Abstract
Purpose :
The aim of this study was to evaluate anterior chamber volume (ACV), iris volume (IV) provided by Anterior Segment Swept Source-OCT (SS-OCT) in healthy subjects and angle closure glaucoma patients.
Methods :
A total of 20 eyes from 20 healthy Chinese subjects with a mean age of 45.5±4.5 years(range:47~65years); and 20 eyes diagnosed with angle closure glaucoma (ACG) from 20 Chinese patients with a mean age of 48.5±7.5 years(range:42~70years) were also enrolled in this study. The anterior chamber volume (ACV) and iris volume (IV) of these subjects were examined using a SS-OCT. The independent samples t test was performed to compare the ACV, IV of the healthy subjects and ACG patients.
Results :
Mean ACV, and IV for all healthy subjects were 152.59±29.96 mm*3(range:171.06~56.61 mm*3)，and 34.20±4.39mm*3(range:19.77~44.42 mm*3). Mean ACV, and IV for ACG patients were 74.70±16.99 mm*3(range:112.89~47.02 mm*3)，and 27.47±6.22mm*3(range:12.75~40.22 mm*3). Significant differences were found between healthy subjects and ACG patients (p<0.05).Compared with healthy subjects, ACG patients had less ACV and IV.
Conclusions :
ACG patients presented a significant decrease in ACV, it maybe manifested that volume of anterior chamber was a good indicator for ACG. The results also suggested that iris atrophy widely existed in ACG patients.
This is an abstract that was submitted for the 2016 ARVO Annual Meeting, held in Seattle, Wash., May 1-5, 2016.