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WONSEOK LEE, Hyoung Won Bae, Samin Hong, Chan Yun Kim, Gong Je Seong; Angle configuration changes and Intraocular pressure reduction in normotensive glaucoma(NTG) after cataract operation.. Invest. Ophthalmol. Vis. Sci. 2016;57(12):5131.
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© ARVO (1962-2015); The Authors (2016-present)
To investigate the change of anterior angle morphology after phacoemulsification with intraocular lens implantation in eyes with cataract using Swept-Source optical coherence tomography(SS-OCT) in normotensive glaucoma(NTG) patients.
Group 1 is the “Normal group” including normal subjects except cataract. Group 2 is the “Normotensive glaucoma group (NTG group)” diagnosed as normotensive glaucoma with cataract. 33 eyes of 27 patients (Group 1) and 22 eyes of 18 patients (Group 2) were performed phacoemulsification with intraocular lens implantation. Before and after the operation, postop 1 day, 1 week and 1 month, the anterior chamber angles were evaluated by SS-OCT(CASIA®, Tomey) under dark conditions using three-dimensional angle analysis scan protocol. In order not to indent eyes, we obtained SS-OCT scans and analyzed with nasal, temporal, superior and inferior quadrant of eyes in naturally eye opening status. AOD, TISA, and TIA were calculated automatically by SS-OCT after the observer marked the scleral spurs. IOP and species of glaucoma medications were also checked before and after cataract surgery. These repeated, longitudinal data were analyzed by SPSS®(IBM®, SPSS® Statistics 20) based on longitudinal-parametric, paired t-test. All patients were included and all the results were meaningful with P<0.05.
Enrolled 45 patients were 23 men and 22 women. The mean age was 68.71±9.82 years. Preoperative means of AOD, TISA, and TIA were 0.51±0.27(mm), 0.21±0.11(mm2), and 28.83±11.51(°). Postop 1day, 1 week and 1month, the means of AOD, TISA, TIA were 0.63±0.19(mm), 0.24±0.08(mm2), 32.05±7.54(°), and 0.67±0.24(mm), 0.26±0.1(mm2), 36.78±8.4(°) and 0.67±0.24(mm), 0.26±0.1(mm2), 36.78±8.4(°). Therefore, angle parameters were increased meaningfully after cataract surgery. Preoperative intraocular pressure was 13.50±2.59(mmHg), and postoperative IOP was 11.42±2.97(mmHg) in NTG group. After the cataract surgery, IOP reduction was obtained in NTG group meaningfully (p=0.003). NTG patients used 1.55±0.61 species of anti-glaucoma eyedrops before surgery, but 0.82±0.73 species after surgery (p=0.005).
The eyes that were performed cataract operation have improved anterior chamber angle parameters and decreased IOP. It could be predicted that cataract surgery can improve aqueous humor dynamic in normotensive glaucoma patients.
This is an abstract that was submitted for the 2016 ARVO Annual Meeting, held in Seattle, Wash., May 1-5, 2016.
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