September 2016
Volume 57, Issue 12
Open Access
ARVO Annual Meeting Abstract  |   September 2016
Fixation instability and amblyopia
Author Affiliations & Notes
  • Eileen E Birch
    Retina Foundation of the Southwest, Dallas, Texas, United States
  • Footnotes
    Commercial Relationships   Eileen Birch, None
  • Footnotes
    Support  NIH Grant EY022313
Investigative Ophthalmology & Visual Science September 2016, Vol.57, No Pagination Specified. doi:
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      Eileen E Birch; Fixation instability and amblyopia. Invest. Ophthalmol. Vis. Sci. 2016;57(12):No Pagination Specified.

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      © ARVO (1962-2015); The Authors (2016-present)

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Presentation Description : Decorrelated visual input from the two eyes during visual development can result in habitual suppression of one eye and amblyopia. Amblyopia can be remediated by rebalancing contrast to overcome suppression, allowing repeated binocular visual experience. Decorrelation during visual development also affects the maturing ocular motor system; amblyopic children have fixation instability. We have identified an association between fixation instability and binocular dysfunction (suppression and abnormal stereoacuity). Ongoing studies in our laboratory are quantifying changes in fixation instability in response to monocular and binocular amblyopia treatments. Whether fixation instability poses a limit to visual acuity improvement that could be eliminated with fixation training is unknown. Fixation instability associated with amblyopia may significantly degrade the child’s performance of daily tasks, including fine motor skills and reading.

This is an abstract that was submitted for the 2016 ARVO Annual Meeting, held in Seattle, Wash., May 1-5, 2016.


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