Abstract
Purpose :
The purpose of this study was to analyze the relationship between sex hormone and IOP in Korean adult females
Methods :
A total of 5032 women, who participated in the Korean National Health and Nutrition Examination Survey from 2010 to 2011. Demographic, comorbidity, and health-related behavior information was obtained via interview. Glaucoma diagnosis was based on criteria established by the International Society of Geographic and Epidemiologic Ophthalmology. IOP was measured by goldmann applanation tonometer. We analyzed the relationship between the age of menarche, age of menopause or childbearing period(interval from menarche to menopause) and IOP or prevalence of glaucoma.
Results :
The prevalence of glaucoma was 3.9% in female. The mean age at menarche was 14.45 (0.04) years. The mean age of menopause was 48.67 (0.15) years. The mean childbearing period was 32.88 (0.16) years. More than 52 age of menopause and more than 35 years of childbearing period has associated with high mean IOP. Any parameters of menarche or menopause did not show association with the prevalence of glaucoma.
Conclusions :
The long menstration period was associated with a higher IOP, but not with prevalence of glaucoma. For more confidence that sex hormone may have a role in IOP or the pathogenesis of glaucoma, prospective studies would need.
This is an abstract that was submitted for the 2016 ARVO Annual Meeting, held in Seattle, Wash., May 1-5, 2016.