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Kara Dolezal, Namratha Turlapati, Marijean Miller; Rate of High Frequency Oscillator Ventilation (HFOV) in Infants with Type 1 Retinopathy of Prematurity (ROP) versus Untreated Controls in a Level IV Nursery. Invest. Ophthalmol. Vis. Sci. 2016;57(12):6305. doi: https://doi.org/.
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© ARVO (1962-2015); The Authors (2016-present)
The purpose of the study is evalute if newborns meeting criteria for ROP screening have a difference in ROP outcomes if managed with standard ventilation versus high frequency oscillatory ventilation.
A control group of infants < 28 weeks gestational age admitted during the ROP screening period was randomly selected from the total set of infants screened from January 2011 to June 2015. A set of infants treated for Type 1 ROP during this time period was compared for summed days on HFOV, days on conventional ventilation (V), and days on non-mechanical ventilation (no-V) support with a denominator of total NICU days to show percentage of time spent on each respiratory support mode.
In the control group of 45 infants, 8 (18%) received HFOV interspersed with days of conventional ventilation, 28 (62%) received only V, and 9 (20%) no-V. In 29 treated for ROP, 3 (10%) received HFOV, 22 (76%) V, and 4 (14%) received no V. Percentage of time spent on each respiratory support mode, control versus treated respectively, were: HFOV 2.5% vs 0.3%; V 20.7% vs 21.6%; and no-V 76.8% vs 78.1%.
HFOV was used more in infants that did not develop Type 1 ROP in a Level IV nursery.At our institution, HFOV is a rescue treatment for critically ill infants rather than a primary ventilation mode. Control infants without Type 1 ROP had more HFOV days in our NICU than did infants treated for Type 1 ROP.
This is an abstract that was submitted for the 2016 ARVO Annual Meeting, held in Seattle, Wash., May 1-5, 2016.
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