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Rony Preti, Maria Fernanda abalem, Rafael Garcia, Helen Nazareth Veloso Santos, Pedro C Carricondo, Leandro C Zacharias, Sérgio Luís Gianotti Pimentel, Remo Susanna, Walter Y Takahashi, Mario L R Monteiro; Foveal choroidal thickness using spectral-domain optical coherence tomography in diabetic patients during the water-drinking test. Invest. Ophthalmol. Vis. Sci. 2016;57(12):6315.
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© ARVO (1962-2015); The Authors (2016-present)
To evaluate the change in foveal choroidal thickness (CT) after the water-drinking test (WDT) using spectral-domain optical coherence tomography (SD-OCT) in diabetic patients.
Prospective, cross-sectional and comparative study. Twenty-six eyes of 13 healthy volunteers (control group) and 30 eyes of 15 diabetic patients (study group) underwent macula scanning using SD-OCT (Spectralis; Heidelberg Engeneering, Heidelberg, Germany software) at baseline and 15, 30, 45, and 60 minutes after the start of the WDT. The WDT consisted of drinking 1000 mL of water within five minutes. Objective measurements of the subfoveal CT were obtained with manual delineation of the choroidal boundaries.
Mean (standard deviation) age of participants was 61.60 (±8.20) years and 7 patients were women. After water ingestion, the mean foveal CT at baseline, 15, 30, 45 and 60 minutes were 284, 304, 322, 306 and 315 µm in the study group and 230, 236, 239, 234 and 231 µm in the control group, respectively. The study group presented a thicker choroid in all time points of the test when compared to the control group (P = 0.015, P = 0.005, P = 0.002, P = 0.002 and P = 0.001). In the study group, foveal CT increased in all time points after water ingestion when compared to baseline and by a maximum of 12% (P < 0.000) at 30 minutes.
A significant increase in foveal choroidal thickness is observed in diabetic patients after the WDT using SD-OCT.
This is an abstract that was submitted for the 2016 ARVO Annual Meeting, held in Seattle, Wash., May 1-5, 2016.
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