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Fatemeh Heidary, Mahmood Nejabat, reza gharebaghi; Correlation Between Central Corneal Thickness and Intraocular Pressure in Children; an Experience from Shiraz, Iran. Invest. Ophthalmol. Vis. Sci. 2016;57(12):6444.
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© ARVO (1962-2015); The Authors (2016-present)
The purpose of this study was to determine normal central corneal thickness (CCT) and intraocular pressure (IOP) in healthy Iranian children as a reference value. Furthermore, the possible correlations between CCT and IOP were analyzed.
A prospective, analytical study on 262 eyes of 131 subjects (6-13 years old primary school Iranian children) without anterior or posterior segment abnormalities, clinical diagnosis of corneal diseases or glaucoma. CCT measured by specular microscopy and IOP précised by Goldmann applanation tonometer (GAT) and non-contact air-puff tonometry (NCT) the correlation of these instruments were analysed, as well.
The mean CCT was 513.47±34.51 micrometer in the right eye (OD) and 513.93± 33.88 micrometer in the left eye (OS). When patients were stratified into two age groups, CCT did not vary with age. Furthermore, the mean IOP by GAT was 13.86±2.13 mmHg and 13.72±2.04 mmHg in OD and OS respectively. However the mean IOP by NCT was 15.26±2.38 mmHg and 15.11±2.18 mmHg in the OD and OS respectively. A positive but week correlation was found between CCT and IOP by GAT (r=0.141 OD, r=0.236 OS). However moderate correlation was found between CCT and IOP by NCT (r=0.487 OD, r=0.456 OS). Once measuring IOP by GAT our findings indicated that for every 100-micrometer increase in CCT, the IOP increased by 0.8 mmHg and 1.4 mmHg in OD and OS, respectively. Nevertheless once measuring IOP by NCT our findings indicated that for every 100-micrometer increase in CCT, the IOP increased by 3.3 mmHg and 2.9 mmHg in OD and OS, respectively. Our results revealed that there was fair agreement between GAT and NCT in OD whereby there was good agreement between GAT and NCT in OS based on analysis by intraclass correlation coefficient (ICC).
CCT and IOP were correlated in healthy school children aged 6-13 years. Based on our findings corneal thickness in Iranian children is one of the thinnest CCT as compare other racial groups.
This is an abstract that was submitted for the 2016 ARVO Annual Meeting, held in Seattle, Wash., May 1-5, 2016.
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