Abstract
Purpose :
We aimed to investigate the incidence of intraocular pressure (IOP) spikes within the first postoperative hours following standard trabeculectomy, and to determine possible associated factors.
Methods :
A multicenter prospective interventional study was carried out. We enrolled consecutive patients undergoing standard trabeculectomy with mytomicin C. Key exclusion criteria were the presence of any other ocular disease (except from cataract) and ocular trauma. All included patients were examined within the first postoperative hours (between hours 1-2 and 4-6), at days 1 and 7. Demographic and ocular data were collected. Main outcomes measurements were IOP values at each time point and the frequency of IOP spikes (defined as IOP≥25 mmHg).
Results :
A total of 32 patients were included (mean age 60.7±13.1 years). Mean preoperative IOP and number of antiglaucoma medications were 22.3±7.8 mmHg and 2.9±0.6, respectively. Although IOP was significantly reduced to 12.1±9.1 mmHg at hour 1-2 (p<0.01) and to 11.5±7.2 mmHg at hour 4-6 (p<0.01), IOP spikes were documented in 10% of the cases within the first postoperative hours (IOP range: 26 – 38 mmHg).
Conclusions :
Our results suggest that although uncommon, IOP spikes may occur in the first postoperative hours following trabeculectomy. We believe that, in selected cases, such as those with advanced disease and fixation threat, first hours postoperative IOP should be measured, for potential IOP spikes identification and treatment, preventing undesirable outcomes
This is an abstract that was submitted for the 2016 ARVO Annual Meeting, held in Seattle, Wash., May 1-5, 2016.