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David R Williams; Seeing through the retina. Invest. Ophthalmol. Vis. Sci. 201657(12):.
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© ARVO (1962-2015); The Authors (2016-present)
Presentation Description :
The correction of the eye’s aberrations with adaptive optics has made it possible to image the retina of the living eye at microscopic resolution. This talk will describe recent developments that combine adaptive optics with other imaging modalities to obtain not only structural but also functional information at a cellular spatial scale. Examples will include single and two-photon fluorescence imaging of individual retinal cells, which allows us to optically probe the electrical signals the retina sends to the brain as well as molecular events in photoreceptors that would otherwise be invisible. These high resolution imaging tools, combined with recent advances in our ability to record from and control neurons with light, could eventually help complete our understanding of the computations the retina performs that allow us to see, and also help to restore vision in the blind.
This is an abstract that was submitted for the 2016 ARVO Annual Meeting, held in Seattle, Wash., May 1-5, 2016.
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