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Priya Patel, A. John Kanellopoulos; Superior and Inferior Corneal Epithelial Long Term Remodeling in Myopic Corrections with Small Incision Lenticule Extraction (SMILE).. Invest. Ophthalmol. Vis. Sci. 2017;58(8):163. doi: https://doi.org/.
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© ARVO (1962-2015); The Authors (2016-present)
To assess the reactive changes of the superior and inferior corneal epithelial thickness profile induced by small incision lenticule extraction (SMILE) for treatment of myopia.
This prospective observational study included 16 eyes that were scheduled for myopic SMILE. Optical coherence tomography (OCT) was applied to measure corneal epithelial thickness superiorly and inferiorly within the central 5-mm zone preoperative and postoperatively at various time points.
The average superior epithelial thickness increased from 51.4 ± 2.9 μm preoperatively to 55.9 ± 4.2 μm 6 months postoperatively and the average inferior epithelial thickness increased from 52.8 ± 3.0 μm to 57.2 ± 3.5 μm respectively. Average epithelial thickness increased 0.84% superiorly and 1.28% inferiorly of the preoperative thickness at 24 hours postoperatively, 2.4% and 4.8% at 1 week, 8.7% and 7.4% at 1 month, 9.6% and 8.4% at 3 months respectively.
In this initial study of corneal epithelial thickness remodeling after myopic SMILE, significant epithelial thickening remains stable 3 months after the treatment superiorly and inferiorly.
This is an abstract that was submitted for the 2017 ARVO Annual Meeting, held in Baltimore, MD, May 7-11, 2017.
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