Abstract
Purpose :
To describe morphological changes in the naïve choroidal neovascularization (CNV) in patients with AMD, after intravitreal treatment with anti-VEGF (IVT), evaluated with OCTA
Methods :
Forty-five eyes were evaluated in 37 patients affected by wet AMD and treated with intravitreal antiVEGF. The morphological characteristics of CNV were assessed by OCT XR Avanti –Optovue before, and 1, 2 and 3 months after injection
Results :
Morphological changes of CNV were already observed after the first month and continued to be observed in subsequent months. Major variations concern the reduction of the area of the lesion; and the serious loss of peripheral capillaries with branching vascular plot that constantly increases after each IVT. In 14 patients the appearance of a feeder trunk was observed even after the first injection. In three eyes that have not been subjected to the third injection, we immediately observed a new increase in capillary density.
Conclusions :
The OCTA allows us to obtain useful morphological information about the significant variations faced by CNV after treatment with antiVEGF IVT, as well as being a very useful and convenient method of non-invasive investigation
This is an abstract that was submitted for the 2017 ARVO Annual Meeting, held in Baltimore, MD, May 7-11, 2017.