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Xiao Yi Zhou, Nariman Nassiri, Di Zhou, Chaesik Kim, Justin Tannir, Anju Goyal, Shukairy Aman, Mark S Juzych, Bret A Hughes; Factors Affecting Conjunctival Erosion Following Ahmed Valve Implantation. Invest. Ophthalmol. Vis. Sci. 2017;58(8):4966.
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© ARVO (1962-2015); The Authors (2016-present)
Conjunctival erosion is a surgical complication of Ahmed valve implantations. The purpose of this study is to identify potential factors associated with conjunctival erosion after Ahmed valve implantation.
This was a retrospective interventional case series of patients who had Ahmed valve implantations between October 2006 and July 2016 at Kresge Eye Institute. Different demographic, clinical and surgical data were collected. The frequency of conjunctival erosion was measured and the association between erosion and different factors were studied by bivariate and logistic analyses.
306 eyes of 277 patients were included in the study. 23 of the 306 eyes (7.52%) had conjunctival erosions. Mean follow-up time was 30.1±30.1 months in the non-erosion group, and 39.8±38.2 months in the erosion group. The mean and median time to erosion was 10.8±16.6 and 5.8 months, respectively. In bivariate analyses, there was no statistically significant difference between erosion and non-erosion groups in all factors except for lens status, having no tube covering and hypertension (Table 1). There was no significant difference in erosion between different patch grafts used to cover the tube (p=0.57) (Table 1&2). Having no tube covering (p<0.01) and aphakia (p<0.01) were significantly more common in the erosion group. On logistic regression analysis we only found aphakia (p<0.01; odds ratio=16.81) to be significantly associated with erosion (Table 2). Having no tube covering was not found to be significantly associated with erosion (p=0.30). Patients who used more than 6 months of topical steroids postoperatively (vs. <6 months) was found to have significantly less erosion (p=0.04; OR=0.12) only in the logistic regression and not the bivariate analysis (p=0.25). Based on bivariate (Table 1) and logistic (Table 2) analyses, association between conjunctival erosion and postoperative steroid use is inconclusive.
We did not find a significant association between several demographic, clinical and surgical factors and conjunctival erosion after Ahmed valve implantation except for aphakia, which was significantly associated with more conjunctival erosion. Further prospective studies are warranted to evaluate different attributing factors to conjunctival erosion.
This is an abstract that was submitted for the 2017 ARVO Annual Meeting, held in Baltimore, MD, May 7-11, 2017.
Table 1. Baseline demographics and clinical characteristics.
Table 2. Logistic regression showing association between conjunctival erosion different factors.
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