June 2017
Volume 58, Issue 8
ARVO Annual Meeting Abstract  |   June 2017
PEDIG Lensectomy Registry: Rates of Amblyopia Treatment, Glaucoma and Other Complications One Year after Surgery
Author Affiliations & Notes
  • Michael X Repka
    Jaeb Center for Health Research, Tampa, Florida, United States
  • Trevano W Dean
    Jaeb Center for Health Research, Tampa, Florida, United States
  • Raymond Kraker
    Jaeb Center for Health Research, Tampa, Florida, United States
  • David K Wallace
    Duke Eye Center, Durham, North Carolina, United States
  • Erick D Bothun
    Mayo Clinic, Rochester, Minnesota, United States
  • Erin D Stahl
    Children's Mercy Hospitals and Clinics, Kansas City, Missouri, United States
  • Scott R Lambert
    Stanford University, Palo Alto, California, United States
  • David G Morrison
    Vanderbile Eye Center, Nashville, Tennessee, United States
  • Footnotes
    Commercial Relationships   Michael Repka, None; Trevano Dean, None; Raymond Kraker, None; David Wallace, None; Erick Bothun, None; Erin Stahl, None; Scott Lambert, None; David Morrison, None
  • Footnotes
    Support  EY011751, EY023198, and EY018810
Investigative Ophthalmology & Visual Science June 2017, Vol.58, 787. doi:https://doi.org/
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      Michael X Repka, Trevano W Dean, Raymond Kraker, David K Wallace, Erick D Bothun, Erin D Stahl, Scott R Lambert, David G Morrison; PEDIG Lensectomy Registry: Rates of Amblyopia Treatment, Glaucoma and Other Complications One Year after Surgery. Invest. Ophthalmol. Vis. Sci. 2017;58(8):787. doi: https://doi.org/.

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      © ARVO (1962-2015); The Authors (2016-present)

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Purpose : There are limited data on outcomes following childhood cataract surgery. We conducted a prospective registry study collecting treatments and complications in the first year following lensectomy.

Methods : Children underwent lensectomy from birth to <13 years of age in at least one eye with follow-up between 6 and 18 months. We determined the rates of postoperative amblyopia treatment, new glaucoma or glaucoma suspect diagnoses, additional same eye surgery and other complications.

Results : 1169 eyes of 911 children underwent lensectomy; 42% were bilateral. 676 (58% of eyes) had an IOL implanted. Amblyopia treatment was prescribed for 427 (47%) patients: 38 (23%) of 165 children with binocular aphakia, 162 (83%) of 195 with monocular aphakia, 35 (16%) of 214 with binocular pseudophakia and 192 (57%) of 337 with monocular pseudophakia. The mean age at time of lensectomy of children treated for amblyopia was 3.6 years (median=2.3; range=0.2 to 13.5).

Glaucoma or glaucoma suspect was diagnosed in 64 (6%) of 1097 eyes that had no preoperative diagnosis of glaucoma. Retinal detachment occurred in 8 eyes (<1%) and endophthalmitis in one eye (<1%). Additional ocular surgery was performed in 196 eyes (17%). Surgery was performed to clear the visual axis in 140 eyes (12%); a laser capsulotomy in 80 (57%) and membranectomy and/or vitrectomy in 62 (44%). Glaucoma surgery was performed in 27 eyes (2%). Twenty-eight (3%) children underwent strabismus surgery.

Conclusions : The most common postoperative intervention after refractive correction was amblyopia treatment. The rate of complications (glaucoma, retinal detachment, endophthalmitis) one year following pediatric lensectomy was low. Additional surgery was performed in about 1 in 6 eyes, most often a laser capsulotomy. Continued follow-up of this cohort is planned through 5 years after surgery.

This is an abstract that was submitted for the 2017 ARVO Annual Meeting, held in Baltimore, MD, May 7-11, 2017.


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