June 2017
Volume 58, Issue 8
ARVO Annual Meeting Abstract  |   June 2017
The use of corneal scrubbing associated with matrix therapy in the treatment of chronic ulcers
Author Affiliations & Notes
  • Lazreg Sihem
    Blida, Cabinet Dr Lazreg, Blida, Algeria
  • didier renault
    clinical trials, laboratoires THEA, Clermont ferrand, France
  • Footnotes
    Commercial Relationships   Lazreg Sihem, None; didier renault, laboratoires THEA (E)
  • Footnotes
    Support  NONE
Investigative Ophthalmology & Visual Science June 2017, Vol.58, 1399. doi:https://doi.org/
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      Lazreg Sihem, didier renault; The use of corneal scrubbing associated with matrix therapy in the treatment of chronic ulcers. Invest. Ophthalmol. Vis. Sci. 2017;58(8):1399. doi: https://doi.org/.

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      © ARVO (1962-2015); The Authors (2016-present)

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Purpose : To enhance corneal healing with scrubbing before treatment with matrix therapy,

Methods : Retrospective study on chronic corneal ulcers evolving for several weeks refractory to conventional treatments methods;
All the corneal ulcers were scrubbed with cotton buds, most of them received matrix therapy at the dose regimen of a drop every other day until corneal healing and preservative free lubricants 3 times a day, for the painful cases, we performed bandage contact lenses, and the remaining patients received the bandage contact lenses without matrix therapy ; ocular examination was performed at D0, D3, D7, D15 and D30, with slit lamp examination, fluorescein coloration and measurement of the size of the ulcers,

Results : 15 patients were included and divided on 3 groups: Group1: n= 6 corneal scrubbing, matrix therapy, lubricant and contact lenses; Group 2: n= 8 corneal scrubbing, matrix therapy, lubricant without contact lenses; Group 3: n= 1 corneal scrubbing; lubricant and contact lenses; All the ulcers healed at D30, in the group1 and 2, corneal healing was faster between 7 and 10[days. No complications were reported despite the occurrence of one case of descemetocele at D3, with a good outcome at D15

Conclusions : Corneal scrubbing may accelerate corneal healing and therefore allows matrix therapy to be more efficient.

This is an abstract that was submitted for the 2017 ARVO Annual Meeting, held in Baltimore, MD, May 7-11, 2017.


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