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Hideaki Someya, Yoshihiro Takamura, Masakazu Morioka, Hiroshi Yokoyama, Takeshi Kimura, Seiji Sameshima, Taiji Sakamoto, Masaru Takeuchi; Comparison of efficacy of vitrectomy and internal limiting membrane peeling for maculopathy involved in proliferative diabetic retinopathy. Invest. Ophthalmol. Vis. Sci. 2017;58(8):2145.
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© ARVO (1962-2015); The Authors (2016-present)
To compare efficacy of vitrectomy and internal limiting membrane (ILM) peeling for tractional maculopathy (TM) and non-tractional macular edema (ME) involved in proliferative diabetic retinopathy (PDR).
Retrospective multicenter observational study. Medical records of patients with PDR and TM or ME, who underwent 25 gauge pars plana vitrectomy with ILM peeling between April 2011 and September 2015 and was followed-up more than 12 months without re-vitrectomy, were reviewed. Visual acuity (VA) in decimal notion converted to minimal-angle-of-resolution scores and central subfield macular thickness (CSMT) before and at 6 and 12 months after surgery were investigated. Mean pre- and postoperative VA and CSMT were compared within each group, and the mean changes in VA and CSMT of TM group were compared to those of ME group.
Seventy-two eyes from 65 patients (41 males and 24 females) with a mean age of 56.8 ± 11.4 years were included, and 47 eyes were classified to TM group and 25 eyes were ME group. VA before and at 6 and 12 months after surgery were 0.91 ± 0.72, 0.51 ± 0.53, and 0.50 ± 0.63 in TM group, and 1.12 ± 0.51, 0.43 ± 0.40, and 0.37 ± 0.34 in ME group. CSMT before and at 6 and 12 months after surgery were 451 ± 154, 302 ±135, and 256 ± 121µm in TM group, and 449 ± 154, 313 ± 117, and 289 ± 118µm in ME group. BCVA and CSMT were significantly decreased at 6 and 12 months in both TM and ME groups. Although there was no statistical difference in the mean change of CSMT between two groups, the mean change of VA in TM group was significantly lower than that of ME group.
The present results indicate that vitrectomy with ILM peeling is effective for tractional maculopathy and non-tractional macular edema involved in PDR, but would be more favorable to non-tractional macular edema.
This is an abstract that was submitted for the 2017 ARVO Annual Meeting, held in Baltimore, MD, May 7-11, 2017.
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