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Mariana Ingolotti, Maria Soledad Ormaechea, Cristobal A Couto, Mario Joaquin Saravia, Bernardo Ariel Schlaen; Outcomes of diagnostic and therapeutic vitrectomy in uveitis. Invest. Ophthalmol. Vis. Sci. 2017;58(8):2814. doi: https://doi.org/.
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© ARVO (1962-2015); The Authors (2016-present)
To assess the outcomes of diagnostic and therapeutic vitrectomy in uveitis
This is a retrospective study. Clinical records of patients who underwent vitrectomy for diagnostic or therapeutic reasons from the department of uveitis of Hospital Universitario Austral were reviewed. Collected data included, age, gender, vitrectomy indication, diagnosis, best corrected visual acuity (BCVA) before and 1 month after the procedure. Sensitivity and specificity was calculated. Chi square to compare proportions and t student test for paired media were used as appropriate.
Thirty three patients (19 male, 14 female) with complete data were included in this study. Average age was 46.82 ± 19.51 years. Vitrectomy was performed for diagnostic reasons in 13 cases, while the procedure was performed for therapeutic reasons in 27 cases. Both reasons led to indicate the procedure in 7 cases. Diagnostic vitrectomy (cytology and bacterial/fungal culture) had a sensitivity of 83% and a specificity of 100%. Therapeutic vitrectomy was performed for the treatment of epiretinal membranes in 6 cases (22.22%), rhegmatogenous retinal detachment in 5 cases (18.52%), persistent vitreous opacities in 5 cases (18.52%), chronic postoperative endophthalmitis in 4 cases (14.81%), tractional retinal detachment in 2 cases (7.41%), and 1 case each of fungal endogenous endophthalmitis, posterior subtenon perforation, vitreo macular traction, and vitreous hemorrhage. Only 19 cases out of 27 had BCVA recorded before and after the procedure. BCVA before the procedure was 20/200 or less in 14 cases (73.68 %), while 1 month after the procedure was 20/200 or less in 10 cases (52.63%). The difference was not statistically significant (chi square = 1.81, P>0.05)
Diagnostic vitrectomy has shown to have a high sensitivity and specificity for detecting either a masquerade syndrome or an infection. Although it was not observed a statistically significant difference between BCVA before and after therapeutic vitrectomy, there was a favorable numerical difference on BCVA after vitrectomy.
This is an abstract that was submitted for the 2017 ARVO Annual Meeting, held in Baltimore, MD, May 7-11, 2017.
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