June 2017
Volume 58, Issue 8
Open Access
ARVO Annual Meeting Abstract  |   June 2017
Optical coherence tomography angiography and “en-face” optical coherence tomography in retinal vein occlusion
Author Affiliations & Notes
  • Alexandros Deligiannidis
    POVISA hospital, Vigo, Spain
  • Daniel Velazquez Villoria
    POVISA hospital, Vigo, Spain
  • jose lorenzo carrero
    POVISA hospital, Vigo, Spain
  • Footnotes
    Commercial Relationships   Alexandros Deligiannidis, None; Daniel Velazquez Villoria, None; jose lorenzo carrero, None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science June 2017, Vol.58, 3675. doi:
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      Alexandros Deligiannidis, Daniel Velazquez Villoria, jose lorenzo carrero; Optical coherence tomography angiography and “en-face” optical coherence tomography in retinal vein occlusion. Invest. Ophthalmol. Vis. Sci. 2017;58(8):3675.

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      © ARVO (1962-2015); The Authors (2016-present)

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Purpose : To evaluate the optical coherence tomography angiography (OCT-A) findings of the superficial and deep capillary plexa in eyes with retinal venous occlusions and compare them with those of
“en-face” OCT.

Methods : This is a retrospective, observational case study. Patients presenting with retinal vein occlusions to a tertiary-level hospital underwent a comprehensive ophthalmic examination. Optical coherence tomography angiography was performed with Topcon's DRI OCT TRITON Swept Source OCT-A system, in 6mm x 6mm regions centered on the fovea. The same system was used to obtain the cross-sectional and “en-face”-OCT microstructural data. Image analysis was performed with the IMAGEnet software, that provided automated retinal segmentation data of the superficial and deep capillary plexa. The same software was used for the manual selection and measurements of the areas of impaired retinal perfusion. Further findings as vascular dilation, retinal edema, hard exudates and shunt vessels were assessed.

Results : In this study 39 patients were enrolled, one of them had bilateral retinal vein occlusion (40 eyes). 2 eyes were excluded because of poor-quality images. 10 had central retinal vein occlusion (CRVO) and the remaining 30 had branch retinal vein occlusion. Seventeen patients (44%) were female, 22 (56%) were male and the mean age was of 67 years. Perifoveal capillary arcade was disrupted in 14 eyes (37%). Impaired perfusion areas were more frequent in the deep capillary plexus ( 34 of 38 eyes, 89%) than in the superficial capillary plexus (24 of 38 eyes, 63%, P< .001) and more extensive ( P< .001). Intraretinal cysts were observed in 21 eyes ( 55%) using the “en-face” OCT and in 11 eyes (29%) using the OCT-A, P< .001. Areas with intraretinal cysts were more extensive when measured with “en-face” OCT than with the OCT-A, P= .037. Shunt vessels were found in 19 eyes (50%), vascular dilation in 33 eyes (87%) and hard exudates in 12 eyes (32%).

Conclusions : In retinal vein occlusion the deep capillary plexus appears to be more frequently and extensively affected compared to superficial plexus. Furthermore, the “en-face” OCT seems to be a better imaging modality to detect intraretinal edema than OCT-A.

This is an abstract that was submitted for the 2017 ARVO Annual Meeting, held in Baltimore, MD, May 7-11, 2017.


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