Purchase this article with an account.
Andrea Sarmento, Adriano Sarmento, Rodrigo Pessoa Cavalcanti Lira; Comparison between a Portable Electronic Device (PED) and Optical Coherence Tomography (OCT) to determine Cup-to-Disc Ratio (CDR) through a non-inferiority trial with masked data analysis. Invest. Ophthalmol. Vis. Sci. 2017;58(8):3974.
Download citation file:
© ARVO (1962-2015); The Authors (2016-present)
We propose a new technology that can help glaucoma screening test and we compare it to results obtained by Optical CoherenceTomography (OCT) for measuring Cup-to-Disc ratio (CDR). We performed a non- inferiority trial with masked data analysis comparing these technologies.
A total of 110 subjects ranging from 18 to 60 years from both genders that met the pre-defined criteria were included. This study was carried out in Recife. Subjects underwent vertical cup-to-discratio (VCDR) evaluations with PED and OCT during a single visit. VCDR measurements were repeated 5 times with each equipmment. Evaluations were done by examiners who did not know previously results obtained from other equipment. Data was collected by the main researcher of this research. The ethics committee approved this study before it started and all research members signed the TCLE agreement. The statistical test employed in this study was Pearson Correlation test.
110 left eyes of individuals ranging from 18 to 60 year (39±13), 66 females were evaluated. The average VCDR values obtained from OCT were 0.47±0.1, while the results obtained from PED were 0.42±0.1. Pearson Correlation test resulted in 0.86 with p<0.001 in both extremities.
There was a strong correlation between results obtained from OCT and PED. The main contributions of this work are: (1) aiding ophthalmologists to give an objective CDR evaluation using a low cost computer system; (2) allowing objective CDR monitoring over time.
This is an abstract that was submitted for the 2017 ARVO Annual Meeting, held in Baltimore, MD, May 7-11, 2017.
This PDF is available to Subscribers Only