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Kyeong Ik Na, Young Kook Kim, Ki Ho Park, Jin Wook Jeoung; Trend-based analysis of retinal nerve fiber layer thickness by optical coherence tomography in eyes with optic disc torsion. Invest. Ophthalmol. Vis. Sci. 2017;58(8):3985.
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© ARVO (1962-2015); The Authors (2016-present)
To investigation the relationship between optic disc torsion and changes of peripapillary retinal nerve fiber layer thickness (pRNFLT) in myopic open-angle glaucoma
One hundred-two patients with myopic open angle glaucoma, with glaucomatous damage confined to a single hemiretina, who were followed up over a 5-year period and had four or more results of optical coherence tomography images. Systemic and ocular findings including optic disc torsion were evaluated. The subjects were divided into three groups according to the presence or absence of optic disc torsion and correspondence with glaucomatous damage and direction of optic disc torsion; optic disc torsion with reverse correspondence group, non-optic disc torsion group, optic disc torsion with correspondence group. The changes of pRNFLT evaluated by trend-based analysis using Cirrus optical coherence tomography (OCT) were compared to determine the relationship between optic disc torsion and change of pRNFLT.
The mean age of subject was 57.17±10.43 years, mean spherical equivalent refractive error was -5.26±2.03 diopters, and mean axial length was 25.72±1.06 mm. Mean follow-up duration was 73.21±12.81 months and mean number of follow-up OCT images was 5.80±1.24. The torsional optic disc with correspondence group showed significantly faster pRNFLT thinning of the glaucomatous damaged hemiretina (-1.53±1.38 µm/year) compared with the non-torsional optic disc (-1.13±1.10 µm/year) and the torsional optic disc with reverse correspondence group (-0.49±0.98 µm/year) (p = 0.021).
Optic disc torsion and glaucomatous damage correspondence may be an important prognostic factor for patients with myopic open angle glaucoma.
This is an abstract that was submitted for the 2017 ARVO Annual Meeting, held in Baltimore, MD, May 7-11, 2017.
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