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Zhixi Li, Zhuoting Zhu, Xiaohu Ding, Mingguang He; Ten-year change of refractive error, anterior chamber depth and axial length in southern Chinese children. Invest. Ophthalmol. Vis. Sci. 2017;58(8):4425.
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© ARVO (1962-2015); The Authors (2016-present)
To evaluate changes in refractive errors (REs), anterior chamber depth (ACD) and axial length (AL) among southern Chinese children over a ten year period.
The first-born twins aged 7 to 15 years old in baseline (2006) from Guangzhou Twin Eye Study with annually visits from 2006 to 2016 were included in this study. Children underwent noninvasive partial-coherence laser interferometry (IOLMaster) before pupil dilation and cycloplegic autorefraction .
A total of 637 participants s underwent comprehensive examinations from 2006 to 2016 (2006 mean [SD] age, 10.66 [2.3] years; 51.3% female). In the longitudinal data, linear mixed models were used to explore changes in outcomes over time. Myopic SE (P<.001) and AL (P<.001) increased at 0.29 diopter/y (95% CI, 0.28 to 0.29) and 0.16 mm/y (95% CI, 0.16 to 0.18) respectively. And females were more likely to get more myopic and longer axial length than males (both P<0.001).There was no significant change of ACD over the follow up period (0.246).
This study show that the important longitudinal changes of RE, ACD and AL in southern Chinese children and myopia is very prevalent among Chinese children.
This is an abstract that was submitted for the 2017 ARVO Annual Meeting, held in Baltimore, MD, May 7-11, 2017.
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