Abstract
Purpose :
To examine central corneal thickness (CCT) and its associated factors in a general population in Russia
Methods :
The Ufa Eye and Medical Study (UEMS) included inhabitants with an age of 40+ years and living in an urban region in the province capital city of Ufa/Bashkortostan and in an rural region in the vicinity of Ufa. The particpants underwent an interview and a detailed ophthalmological examination including refractometry and biometry.
Results :
The study included 1087 individuals with a mean age of 61.7 ± 10.4 years (range: 40 to 91 years) and a mean axial length of 23.1 ± 1.29mm (range:19.0-29.3mm). Thicker CCT (mean: 538±38µm; median:538µm;range:344-657µm) was associated (multivariate analysis) with younger age (P<0.001; regression corefficient r= -0.12) and lower keratometric readings (P=0.04;r=-0.07). It was not significantly associated with gender (P=0.94), level of education (P=0.06), axial length (P=0.36), and anterior chamber dpeth (P=0.89). Intraocular pressure readings (Goldmann applanation tonometry) were correlated (P<0.001;r=0.34) with CCT: IOP(mmHg)=0.04xCCT(µm)-6.75.
Conclusions :
CCT was slightly thinner in the South Russian UEMS study population than in Western European populations and thicker than in Indians or Afro-Americans. As in other populations, CCT was not associated with axial length, while intraocular pressure readings depends on CCT.
This is an abstract that was submitted for the 2017 ARVO Annual Meeting, held in Baltimore, MD, May 7-11, 2017.