Inter-device comparison of retinal sensitivity assessments in a healthy population: the CenterVue MAIA and the Nidek MP-3 microperimeters

Abstract

Purpose : To compare and correlate the retinal sensitivity measurements obtained with the Nidek MP-3 and the CenterVue MAIA microperimeters in healthy subjects.

Methods : In this IRB approved, prospective comparative study, 31 eyes of 23 subjects underwent complete ophthalmological examination including retinal sensitivity assessments using two microperimeters, the MP-3 (Nidek Technologies) and the MAIA (CenterVue). The mean retinal sensitivity (dB) and its corresponding luminance (asb) and contrast (log units) were analyzed between the two instruments using Paired Student’s t-tests. The inter-device reproducibility was assessed using intraclass correlation coefficient, and level of agreement of the sensitivity values between the devices was analyzed by Bland–Altman test. Pearson’s analysis was performed to evaluate the association of retinal sensitivity measurements with age, gender and spherical equivalent of the refractive power.

Results : The mean retinal sensivity (dB) measured by the MP-3 (25.08 ± 0.92 dB) was significantly (p < 0.0001) lower compared with the MAIA (30.72 ± 0.77 dB). The luminosity levels were significantly (p <0.0001) higher with the MP3 (7.47 ± 0.80 asb) compared with the MAIA (0.93 ± 0.17 asb). The contrast sensitivity was significantly higher for the MP-3 (0.92 ± 0.33 log units) compared with the MAIA (0.25 ± 0.13 log units). This translated to a mean difference between the MAIA and MP-3 of 5.64 dB, - 6.54 asb and - 0.67 log units for retinal sensitivity, luminance and contrast sensitivity, respectively. Despite these absolute differences, the intraclass coefficient was 0.85 (95% confidence interval [CI]: 0.71-0.92) between the two devices, and after applying a standard correction factor to each data point (MAIA sensitivity = MP-3 sensitivity + 5.64), the mean difference in retinal sensitivity between devices was 5.64 dB.

Conclusions : Retinal sensivity measures higher, but luminance and contrast sensivity measure lower for MAIA-generated values compared with the MP-3. The relationships, however, appeared fairly consistent, and application of a standard correction factor allowed the data to be inter-related, at least for normal eyes.

This is an abstract that was submitted for the 2017 ARVO Annual Meeting, held in Baltimore, MD, May 7-11, 2017.