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Anna Leszczynska, Karolin Moehler, Eberhard Spoerl, Lutz E Pillunat; Investigation of dislocation of the eyeball in patients with endocrine ophthalmopathy with the Dynamic Scheimpflug Analyzer. Invest. Ophthalmol. Vis. Sci. 2017;58(8):5158. doi: https://doi.org/.
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© ARVO (1962-2015); The Authors (2016-present)
The purpose of this study was to investigate the dislocation of the eyeball in patients with endocrine ophthalmopathy (EO) compared to healthy subjects.
In 39 patients with EO and 39 healthy subjects the biomechanical response parameters were measured with the Dynamic Scheimpflug Analyzer Corvis ST (OCULUS, Wetzlar, Germany). Only the right eye served for analysis. A score for severity was included. Statistical analysis was performed with SPSS 23. Data are given as median and interquartile range.
There were no differences in the age within the two groups (54.0±11.5 years; 54.3±11.6 years). Between the group of EO-patients and the control group there were statistically significant differences in intraocular pressure [IOP] 17 mmHg (15.6/19.3) 14.5 mmHg (13/16) (P=0.001), stiffness parameter [SP-A1] 124.7 (111.9/147.8) 110.8 (97.6/122.6) (P=0.001) and the whole eye movement [WEM µm] 197.0 µm (165/255.3) 319.5µm (282.6/347.8) (P=0.001), whole eye movement time [WEM ms] 20.8 ms (19.9/21.4) 21.8 ms (21.5/22.3) (P =0.001). No statistical significant difference was measured in the central corneal thickness, deformation amplitude max, deflection amplitude max, deflection amplitude 2 mm ratio. The severity of the disease does not influence these parameters.
In EO patients the dislocation is reduced. This can be quantified with the Dynamic Scheimpflug Analyzer with the parameter whole eye movement. This parameter characterizes the condition behind the eyeball within the orbit.
This is an abstract that was submitted for the 2017 ARVO Annual Meeting, held in Baltimore, MD, May 7-11, 2017.
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