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Koji Kakisu, Jun Shimazaki, Takefumi Yamaguchi, Yoshiyuki Satake, Daisuke Tomida; The influence that the temperature change of the donor cornea gives to corneal endothelium transplant postoperative endothelium cell density. Invest. Ophthalmol. Vis. Sci. 2017;58(8):5703.
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© ARVO (1962-2015); The Authors (2016-present)
Postoperative problems on Descemet’s stripping automated endothelial keratoplasty (DSAEK) include a decrease in corneal endothelium cell density (ECD) and the corneal endothelium malfunction with it, and it is suggested that the temperature change of the donor cornea affects the rate of decline of the ECD after the DSAEK. In DSAEK using overseas donor cornea, we examine the influence that the preoperation temperature change of the donor cornea gives to postoperative ECD.
74 eyes of 74 patients that undergone DSAEK using overseas donor cornea were enrolled. 37 donor cornea were stored in a low temperature state until before operation, and other 37 were returned to room temperature to calculate ECD, and return into low temperature again before operation. 8 Fuchs corneal endothelium distrophy eyes (18.9%), 10 bullous keratopathy eyes after laser iridotomy(27.0%), 12 bullous keratopathy eyes after cataract surgery(32.4%), 7 endothelial decompensation (reDSAEK) eyes after bullous keratopathy eyes (32.4%), were enrolled.The operation was carried out by the double glide method in all cases. We retrospectively investigated the ECD rate of decline between two groups after DSAEK in 1,3,6 month.
The ECD rate of decline between two groups did not accept significant difference after operation in 1.6 months, but recognized significant difference after operation in three months.
The possibility that the temperature change of the donor cornea had an influence on the early endothelium survival after DSAEK was suggested.
This is an abstract that was submitted for the 2017 ARVO Annual Meeting, held in Baltimore, MD, May 7-11, 2017.
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