Abstract
Purpose :
To compare the effect of the digital fundus camera (DFC) versus scanning laser ophthalmoscope (SLO) indocyanine green angiography (ICGA)-guided photodynamic therapy (PDT) on the treatment of chronic central serous chorioretinopathy (CSC)
Methods :
The data of 38 eyes of 37 patients with chronic CSC were retrospectively reviewed. Choroidal hyper-permeability lesion was assessed in late phase ICGA images using both DFC and SLO type machines. Subjects were divided to DFC and SLO groups, regarding the method to determine the choroidal hyper-permeability lesion. Half-fluence PDT (25J/cm2) was performed in all eyes. Outcome measures included the greatest linear diameter (GLD), best-corrected visual acuity (BCVA) and central macular thickness (CMT).
Results :
Sixteen and 22 eyes were in the DFC and SLO groups, respectively. Baseline parameters did not differ between both groups. GLD was 4013 ± 931 μm and 3314 ± 979 μm in DFC and SLO group, respectively. GLD of DFC group was larger than that of SLO group (p = 0.042). Follow up BCVA (logMAR) significantly improved at 3 months in DFC group, and at 6 months in SLO group, compared to baseline BCVA (p = 0.002 and 0.003, respectively). Mean CMT significantly improved at all follow-up visit in both groups (p < 0.001). The subretinal fluid disappeared in all eyes of DFC group, but remained in 2 eyes (9 %) of SLO group.
Conclusions :
DFC ICGA image showed the larger choroidal hyper-permeability lesion in late phase than SLO ICGA image, which induced to treat the greater area in DFC ICGA guided PDT. This may influence the anatomical and visual outcomes of treatment for chronic CSC.
This is an abstract that was submitted for the 2017 ARVO Annual Meeting, held in Baltimore, MD, May 7-11, 2017.