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Seul Ki Bang, Eung-Suk Kim, Seung-Young Yu; Irregular Pigment Epithelial Detachment in Chronic Central Serous Chorioretinopathy : SD-OCT and OCTA Findings. Invest. Ophthalmol. Vis. Sci. 2017;58(8):5941.
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To evaluate the prevalence of irregular pigment epithelial detachment (PED) in chronic central serous retinopathy (CSC) and to identify the incidence of neovascular change in patients with CSC during the follow-up.
The review of medical records of 142 eyes with chronic CSC which were examined in the Ophthalmology Department of Kyunghee University Hospital retrospectively. Analyzing SD-OCT, fluorescein angiography (FA) and indocyanine green angiography (ICGA) and optical coherence tomography angiography (OCTA) findings.
47 eyes of 142 eyes (33.1%) showed irregular PED on macular OCT finding. The mean age was 53.45 years in irregular PED group and 49.73 years in non-irregular PED group. 12 eyes of 47 eyes (25.5%) was occurred neovascular change during the follow-up, especially 9 eyes in CNV and 3 eyes in PCV. Mean duration at onset of neovascular change was 41.83±46.28 months. To compare between eyes with and without neovascular change in patients with irregular PED, follow-up duration of neovascular change group was 45.25 months and control group was 21.46 months. There was significantly difference between the group (p=0.009). The presence of optically filled sub-RPE space was 11 eyes (91.7%) in neovascular change group and 14 eyes (40.0%) in control group. There was significantly difference between the group (p=0.011). Type 1 neovascular networks were detected in 5 out of 8 eyes (67.5%) on En face OCTA(3x3mm).
The presence of irregular PED and the opacity of sub-RPE space was significant correlation with neovascular change. Also, OCTA was useful diagnostic tool for type 1 neovascularization as much as dye injection angiography.
This is an abstract that was submitted for the 2017 ARVO Annual Meeting, held in Baltimore, MD, May 7-11, 2017.
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