July 2018
Volume 59, Issue 9
Open Access
ARVO Annual Meeting Abstract  |   July 2018
Vitreous visualization: a comparison between ultrasound and OCT widefield
Author Affiliations & Notes
  • Ugo Nava
    Luigi Sacco Hospital University of Milan, Milan, Italy
  • Federico Corvi
    Luigi Sacco Hospital University of Milan, Milan, Italy
  • Lucia Pace
    Luigi Sacco Hospital University of Milan, Milan, Italy
  • salvatore parrulli
    Luigi Sacco Hospital University of Milan, Milan, Italy
  • Matteo Giuseppe Cereda
    Luigi Sacco Hospital University of Milan, Milan, Italy
  • Giovanni Staurenghi
    Luigi Sacco Hospital University of Milan, Milan, Italy
  • Mariano Cozzi
    Luigi Sacco Hospital University of Milan, Milan, Italy
  • Maria Belotti
    Luigi Sacco Hospital University of Milan, Milan, Italy
  • Footnotes
    Commercial Relationships   Ugo Nava, None; Federico Corvi, None; Lucia Pace, None; salvatore parrulli, None; Matteo Giuseppe Cereda, Alcon (F), Bayer (C); Giovanni Staurenghi, Alcon (C), Allergan (C), Bayer (C), CenterVue (F), Genentech (C), Heidelberg Engineering (C), Nidek (F), Novartis (F), Ocular Instruments (P), Optos (F), Optovue (F), Quante Medical (F), Roche (C), Zeiss (F); Mariano Cozzi, None; Maria Belotti, None
  • Footnotes
    Support  none
Investigative Ophthalmology & Visual Science July 2018, Vol.59, 275. doi:
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      Ugo Nava, Federico Corvi, Lucia Pace, salvatore parrulli, Matteo Giuseppe Cereda, Giovanni Staurenghi, Mariano Cozzi, Maria Belotti; Vitreous visualization: a comparison between ultrasound and OCT widefield. Invest. Ophthalmol. Vis. Sci. 2018;59(9):275.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : To compare the effectiveness of ultrasound versus OCT widefield to recognize adherence status between vitreous and retina, and to identify anatomical features of the vitreous body.

Methods : 38 eyes of 19 consecutive patients were included from Luigi Sacco Hospital Eye Clinic, University of Milan. Ultrasound pictures and movies were recorded in transverse and sagittal scans with Aviso Ultrasound Platform (Quantel Medical, Cournon d’Auvergne, France). Widefield OCT images were taken with HRA Spectralis Spectral domain OCT (Heidelberg Engineering, Heidelberg, Germany) and PLEX Elite 9000 Swept-Source OCT (Zeiss, Oberkochen, Germany). In the former 55° lens has been used and single line pictures captured in neutral, left and right gaze. In the latter, we applied a prototype +20 diopter lens focused on posterior pole obtaining single line widefield images in neutral gaze. Pictures were collected, anonymized and examined by two different readers, one reader made two different readings of the same images. Vitreous adhesion status to the retina was classified as fully adherent, partially or totally detached. OCT images were classified adopting vitreous OCT staging system described by Johnson. Readers were also requested to recognize vitreous anatomic details (lamellae, Martegiani’s prepapillary space, bursa premacularis and Cloquet’s canal).

Results : The agreement between the two readers for the vitreous adhesion status was 87% with HRA Spectralis, 91% with PLEX Elite 9000 and 60% with ultrasound. The agreement between two readings of the same operator was 96%, 96% and 75% respectively. There were no statistically significant differences between the OCTs to determine vitreous adhesion status (p=0.265) and staging (p=0.490) but significant differences were found when compared with ultrasound (p<0.01). Anatomical details were appreciated in OCT images with both machines with a mean agreement of 70% between two readers and 90% between the readings of the same reader. No anatomical details were identified with ultrasound.

Conclusions : OCT widefield provides a fast and reliable exam in the vitreous evaluation. The great capacity of anatomical details identification consent not only to determine the adherence status to the retina but also to investigate in vivo internal anatomical structures.

This is an abstract that was submitted for the 2018 ARVO Annual Meeting, held in Honolulu, Hawaii, April 29 - May 3, 2018.

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